Posted: February 8th, 2015

AUtomatic software interpretation of 24 hour impedance pH tracing: is it a mature technology

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Background:

• 24-hour multichannel intraluminal impedance and pH (MII-pH) allows detection of both acid and non-acid reflux (NAR) episodes.
• There is a concern in the community about complexity of interpretation of 24-hr MII-pH tracings, the amount of time a gastroenterologist may

have to spend analyzing these tracings, as well as the reliability of the automatic analysis provided by the different softwares made available by

the manufacturers.

Results:

• The graph summarizes results of correlation between the interpretation of the

expert and the automatic softwares, giving us the Pearson r for each pair.

• For all these data points, we had p<0.0001.
• These results show a very strong correlation between both the expert

interpretation and the automatic analysis.

• When looking at whether the overall interpretation resulted in either a normal or an

abnormal study, the automatic software and the expert agreed 93% of the time for

the Sandhillsoftware and 95% of the time for the MMS software.

Conclusion:

• Our study shows a very strong correlation between the interpretation

provided by an expert and the automatic software analysis for 24-hr.

• However, there is not a total agreement all the time. These softwares are

clearly very reliable at this time, but we would still recommend that the

interpreting physician looks at the tracings before signing off the report

to detect any possible problems such as probe malfunction.

Methods:

• Review of 200 consecutive MII-pH studies on once or twice a day PPI therapy
• 65% females, mean age 48.6yrs.
• 100 done using MMS equipment and recent software (MMS version V 8.19h).
• 100 were done using Sandhill equipment and recent software (Bioviewanalysis

version 5.5.4.1).

• All studies performed between 09/2009 and 9/2012.
• All tracings were interpreted by the same expert with an experience of having read

more than 1500 MII-pH studies.

• For the purpose of this study, a trainee with no experience in interpreting these

tracings collected the data from the expert analysis and then reset the tracings to

their original status prior to modification by the expert, and applied automatic

analysis using the newer versions of the softwares.

Automatic software interpretation of 24-hour impedance pH

tracings: is it a mature technology?

Aim:

• To assess the reliability of 2 different types of 24-hr MII-pH analysis softwares

compared to the interpretation provided by an expert

Mouhamed A. Sabouni1

, Mohamad Ghalayini1

, Sonia Brar1

,Nasser Hajar2

, Amine Hila1

1. Department of Gastroenterology, United health services, Johnson City, NY, United States.
2. Gastroenterology, SUNY Upstate Medical University Hospitals, Syracuse, NY, United States.

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