Posted: February 2nd, 2015
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The study has used ‘ROC curves’ to analyse the impact of the molecular diagnostic test results. Please describe/explain the ‘ROC curve’ using one of the figures in the paper as an example. What are the benefits and limitations of using the ‘ROC curve’ in this way? (15 marks)
Among the various parameters used to describe the value of diagnostic test results (sensitivity, specificity, positive predictive value, negative predictive value, positive and negative likelihood ratio and accuracy), which do you think would be most appropriate in this scenario? Please explain your reasons? How would such a test result influence clinical practice? (10 marks)
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