Posted: September 16th, 2017
Evaluation of a drug study (graduate nurse practitioner
Evaluation of a drug study (graduate nurse practitioner
Order Description
Please find a drug study (mental health related preferred)on Methylcolbalamin (B12) and address the following questions
Research – Community Drug Study
.
Review a drug study on a complimentary medicine using the format below [copy and paste onto your document] answering all the questions thoroughly.
Evaluating Research
Ethical: safety of pt, consent obtained
Statement of Objectives: goals clearly defined
Experimental methods: appropriate to study goals, accuracy and reliability of the methods
Statistical methods: How were patients selected, were there enough patients, do the patients represent the population who will be using the drug, long term study how
many lost to follow up & how was this accounted for, placebo, how were patients assigned to groups, were patients receiving other therapies during the trial & how was
this accounted for, appropriate statistical tests. Patients that dropped out what was the reason?
Conclusions: Data if sound justify conclusions, does the drug offer significant advantages of cost, efficacy, safety over existing agents? Was the objective reached or
did it change in the conclusion? What are your conclusions of this study weaknesses, strengths etc. Statistical values p, CI etc……
P value is significant when it less than 1 in 20 or expressed as P<0.05. This means that if the study was repeated 20 times at least 19 out of 20 would yield
conclusions similar to those observed by the researchers. Any difference no matter how small may be found to be statistically significant if the sample size is large
enough. A STATISTICALLY SIGNIFICANT RESULT, HOWEVER MAY NOT BE CLINICALLY SIGNIFICANT. An outcome is said to be clinically significant if it makes enough difference to
both patients and providers to change current practice.
Research – Community Drug Study
.
Review a drug study on a complimentary medicine using the format below [copy and paste onto your document] answering all the questions thoroughly.
Evaluating Research
Ethical: safety of pt, consent obtained
Statement of Objectives: goals clearly defined
Experimental methods: appropriate to study goals, accuracy and reliability of the methods
Statistical methods: How were patients selected, were there enough patients, do the patients represent the population who will be using the drug, long term study how
many lost to follow up & how was this accounted for, placebo, how were patients assigned to groups, were patients receiving other therapies during the trial & how was
this accounted for, appropriate statistical tests. Patients that dropped out what was the reason?
Conclusions: Data if sound justify conclusions, does the drug offer significant advantages of cost, efficacy, safety over existing agents? Was the objective reached or
did it change in the conclusion? What are your conclusions of this study weaknesses, strengths etc. Statistical values p, CI etc……
P value is significant when it less than 1 in 20 or expressed as P<0.05. This means that if the study was repeated 20 times at least 19 out of 20 would yield
conclusions similar to those observed by the researchers. Any difference no matter how small may be found to be statistically significant if the sample size is large
enough. A STATISTICALLY SIGNIFICANT RESULT, HOWEVER MAY NOT BE CLINICALLY SIGNIFICANT. An outcome is said to be clinically significant if it makes enough difference to
both patients and providers to change current practice.
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