Posted: March 5th, 2015
Introduction
Describe the role of the thymus and the spleen in the immune response. Is it a primary or secondary lymphoid organ? Make sure that you cite references in the text
where appropriate.
(maximum 300 words)
Methods
Present an extremely brief overview of the methods used demonstrating an understanding of the processes involved.
(maximum 300 words)
Results
There is no maximum word count for the results section
Present the fully labelled diagrams you have made of your sections 1-4. Make sure that you include the level of magnification in the figure legend
For sections 1 and 2, provide some explanatory text of the features that you have identified on the sections 1 and 2. Identify at a minimum the T cell and B cell
zones, germinal centre, capsule, red pulp, trabeculae in the spleen and the cortex, medulla, cortico-medullary junction and capsule in the thymus
In the case of sections 3 and 4, identify differences in the appearance of these sections when compared with the healthy tissue examined on slides 1 and 2. Comment on
these differences in this section.
Discussion:
Give reasons for identifying your sections. Discuss from which of the three animal models listed above that you think your sections have been obtained and why. Give
reasons why your sections can not have been derived from mice with the remaining two pathologies. Use references wherever necessary.
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