Posted: September 13th, 2017

human catalase and glutathione peroxidase

human catalase and glutathione peroxidase
Discuss about human catalase and glutathione peroxidase, the importance as antioxidant enzymes. Also mention what happens if somebody has catalase or glutathione peroxidase deficiency and mutation?
genetic information related to catalase and glutathione peroxidase.
general information about AAPH (2,2′-Azobis(2-methylpropionamidine) dihydrochloride).

The effect of AAPH on catalase and glutathione peroxidase antioxidant activities in protecting red blood cells against free radicals such as reactive oxygen species.
Which antioxidant (catalase or glutathione peroxidase) is more effective in protecting human red blood cells against free radicals and relate that to human diseases and why?.

Catalase and glutathione peroxidase activities in removing H2O2 form the human body. And evaluate each enzyme and argue which one (catalase enzyme or glutathione peroxidase enzyme) is better in removing H2O2 and protecting red blood cells against free radicals and why. You can get this information from current studies.
Substrate concentration (H2O2) is low which enzyme (catalase or glutathione peroxidase) will be more effective in the removal of H2O2? And how this process occurs? And what if the substrate concentration is high?
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