Posted: February 20th, 2015

Human Disease Pedigree Analysis Report

Human Disease Pedigree Analysis Report

For this project, the student will be expected to prepare a human pedigree detailing the inheritance of a single genetic disease/disorder. The pedigree must have at

least five generations and include examples of all of the symbols associated with pedigree analysis including living/deceased familial members, disease trait carriers

v/s fully afflicted individuals, and male v/s female members. The pedigree must show at least two marriage events and each familial generation must be labeled as is

customary for authentic human pedigrees. After depicting the disease on the pedigree, a brief 2-3 sentence explanation of the disorder, its dominant or recessive

inheritance pattern as well as its autosomal or sex-linked position in the human genome should be indicated in this brief summary. Also, a brief description of the

manifestations and clinical outcomes of the disease should also be included. This assignment is to be drafted in powerpoint or some other graphics program and uploaded

through the assignments folder by the date indicated in the syllabus. This assignment is worth 100 points (25 points for the five-generation pedigree, 25 points for

the correct use of pedigree annotation and labeling, 25 points for the appropriate depictions of the inherited disease or disorder on the pedigree, and 25 points for

the writeup at bottom of pedigree detailing dominant v/s recessive and autosomal v/s sex-linked inheritance patterns). I suggest you use the many supplementals in the

course content that detail how to construct pedigrees.

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