Posted: February 1st, 2014
The length of telomeres is completely determined by the number of divisons a cell has gone through and accurately predicts age
114. The length of telomeres is completely determined by the number of divisons a cell has gone through and accurately predicts age. T/F
115.-117 What are three reasons given why stem cell therapy might not work in older people (assuming we can get it (except for a few specific conditons) to work period)?
118.-119. In studies of wild mice vs laboratory-bred mice, calorie restriction was not found to have a life-lengthening effect so mice actually lived a shorter time- could you come up with a possible reason?
. (an aside – the evidence that resveretrol, the supposed life-extending chemical found in red wine (among other places) is not believed to be a natural stimulator of sirtuins).
120. What is a property of rapamycin that might NOT make it ideal for extending human lifespan and why?
121. – 123. Define and describe “immunosenescence”. Why might it be beneficial (though I don’t believe it) to an older person?
124. – 126. What is meant by a signaling pathway? What is a protein kinase and how are protein kinases it involved in signaling within a cell
127. – 136. What are reactive oxygen species and how are they believed to be involved in aging?
137. – 142. What are non-cycling cells – what state are they said to be in and can they be brought out of it? How?
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